Experimental animal models of coronary microvascular dysfunction
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چکیده
منابع مشابه
Experimental animal models of neurogenic bladder dysfunction.
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متن کاملPharmacotherapy for coronary microvascular dysfunction.
Coronary microvascular dysfunction (CMD) has been increasingly recognized as an important cardiac condition that can cause signs and symptoms of myocardial ischaemia in various clinical settings. The dysfunction is located on the level of the coronary microcirculation with a vessel diameter of <500 µm and can be characterized by structural as well as functional vascular alterations. The underly...
متن کاملCoronary microvascular dysfunction: an update.
Many patients undergoing coronary angiography because of chest pain syndromes, believed to be indicative of obstructive atherosclerosis of the epicardial coronary arteries, are found to have normal angiograms. In the past two decades, a number of studies have reported that abnormalities in the function and structure of the coronary microcirculation may occur in patients without obstructive athe...
متن کاملCoronary microvascular dysfunction, microvascular angina, and treatment strategies.
Angina without coronary artery disease (CAD) has substantial morbidity and is present in 10% to 30% of patients undergoing angiography. Coronary microvascular dysfunction (CMD) is present in 50% to 65% of these patients. The optimal treatment of this cohort is undefined. We performed a systematic review to evaluate treatment strategies for objectively-defined CMD in the absence of CAD. We inclu...
متن کاملMicrovascular dysfunction in chronic total coronary occlusions.
BACKGROUND Microvascular dysfunction is defined as reduced coronary flow reserve in the absence of an epicardial stenosis. This study determined its prevalence and relation to regional myocardial function in chronic total coronary occlusions (TCO). METHODS AND RESULTS After recanalization and stenting of a TCO (duration, >4 weeks) in 42 patients, coronary flow velocity reserve (CFVR) was meas...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2020
ISSN: 0008-6363,1755-3245
DOI: 10.1093/cvr/cvaa002